产品货号：
Z34675
中文名称：
LCK抗体
英文名称：
Anti-LCK Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LCK Antibody |
| 指标别名 | LCK;LSK;p56 LCK;p56lck;pp58lck;Protein YT16;Proto oncogene Lck;Tyrosine protein kinase Lck;YT16 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,IP,FCM |
| 基因名称 | LCK |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Lck The Src family of protein tyrosine kinases,which includes Src,Lyn,Fyn,Yes,Lck,Blk,and Hck,are important in the regulation of growth and differentiation of eukaryotic cells.Src activity is regulated by tyrosine phosphorylation at two sites,but with opposing effects. |
| 实际分子量 | 58KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Lck (or lymphocyte-specific protein tyrosine kinase) is a 56kDa protein that is found inside specializedcells of the immune system called lymphocytes.The human LCK gene is mapped to chromosome 1p35-p32.This gene is a member of the Src family of protein tyrosine kinases (PTKs).The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells.It contains N-terminal sites for myristylation and palmitylation,a PTK domain,and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs,respectively.The protein localizes to the plasma membrane and pericentrosomal vesicles,and binds to cell surface receptors,including CD4 and CD8,and other signaling molecules.Multiple alternatively spliced variants,encoding the same protein,have been described. |
| Uniprot ID | P06239 |
| 推荐稀释比 | Western blot (WB) 1:400～800 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
相关搜索：LCK抗体，LCK单抗，Anti-LCK Antibody